"Sequential Volumetric Modulated Arc Therapy (VMAT) Boost in Hy- brid Plan With Tangential Beams for Whole Breast Treatment: a Do- simetric Study "

"Purpose: Whole breast radiation therapy (WBRT) with a boost to the tumor bed following con-servative primary surgery in women cancer (BC) plays central role reducing local recurrences and mortality. Volumetric modulated arc (VMAT) technique has been shown allow better dose conformation low levels organs at risk (OARs), compared static fields three-dimensional Conformal Radiotherapy (3D-CRT). The aim of this study was evaluate feasibility dosimetric advantages sequential (SB), administered VMAT tech-nique hybrid plans tangential beams for whole treatment. Material methods: BC patients undergoing adjuvant RT from June October 2020 were selected. ESTRO guidelines Clinical Target Volume (CTV) delineation used. Total delivered 60-66 Gy; 50 Gy 2 daily fractions 10-16 fractions. Results: analysis included 31 treated surgery. Hybrid treatment characterized by 3D-CRT plan using medi-olateral lateromedial irradiation Planning (PTV) coplanar arches PTV gener-ated. Dosimetric resulted homogeneous target volumes coverage OARs constraints compliance. As regarding risks contralateral breast, ipsi- lung heart values analysed. Conclusions: In frame RT, showed that performed techniques are feasible terms outcomes. "